Dr. Chang Yeop Han, PhD, is first author and Dr. Alan Chait, MD, is senior author on the article article entitled “Serum amyloid A impairs the anti-inflammatory properties of HDL”, published in the December 2015 issue of The  Journal of Clinical Investigation. The article reports findings indicating that inflammation results in a loss of the antiinflammatory properties of HDL on adipocytes, which appears to partially result from the SAA component of HDL binding to cell-surface proteoglycans, thereby preventing access of HDL to the plasma membrane. Other UW Diabetes Institute investigators co-authoring the paper include Chongren Tang, PhD, Baohai Shao, PhD, Savitha Subramanian, MD, Tomas Vaisar, PhD and William Osborne, PhD.