Clinical Research Unit Current Studies

WEBS: Weight Effects on Brain Health Study
This study seeks to achieve a better understanding of the role of the brain in successful obesity treatment (surgical and lifestyle). PI: Ellen Schur, MD, MS

Brain Effects on Appetite and Metabolism Study
This study examines if structural brain changes related to obesity play a role in the central regulation of appetite and weight gain in children. PI: Ellen Schur, MD, MS

BIGR: Brain Inflammation and Glucose Regulation The purpose of this study is to learn more about the differences in brain structure in people with and without Type 2 Diabetes and if these differences impact regulation of blood sugar over time. PI: Ellen Schur, MD, MS

This study is to compare how well 2 medicines work and how safe they are in people with type 2 diabetes: 1) fast-acting insulin aspart (a new medicine) and 2) NovoLog® (a medicine doctors can already prescribe). PI: Subbulaxmi Trikudanathan, MD

The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL), which is built into the 670G insulin pump, in adult and pediatric patients with type 1 diabetes in a home setting. PI: Irl Hirsch, MD

The primary purpose of this study is to determine whether sotagliflozin taken orally once daily lowers hemoglobin A1C better than for the treatment of Type 2 diabetes in patients with moderate kidney problems. PI: Subbulaxmi Trikudanathan, MD