News & Events

UWMDI Investigator, Dr. Vincenzo Cirulli, MD, PhD and Albert Folch, PhD, Professor of Bioengineering have received an Innovative Pilot Award supported by WA State funds to the ISCRM.

The project will focus on the development of 3D printed gradient generators emulating in vivo-like morphogen gradients to guide stem cell differentiation into functional pancreatic islet cells. Current protocols for the derivation of pancreatic islet β-cells from stem cells remain relatively inefficient. To help advance the field of islet cell transplantation, the researchers will test

Read More

UWMDI Investigator Kimberly Alonge, PhD, awarded ADA Fellowship

Dr. Kimberly Alonge has been awarded a Postdoctoral Fellowship award from the American Diabetes Association for her project entitled “Novel role of hypothalamic extracellular matrices in the pathogenesis of type 2 diabetes.” This 3-year project seeks to advance the understanding of the functional significance of sulfated hypothalamic glycosaminoglycans in mediating blood glucose homeostasis. Dr. Alonge

Read More

UWMDI Investigator Kimberly Alonge, PhD, recipient of ITHS Early Investigator Catalyst Award

The Institute of Translational Health Sciences has awarded Dr. Kimberly Alonge an Early Investigator Catalyst Award for her project entitled “Investigation of hippocampal heparan sulfates in association with cognitive decline in obesity and T2D.” This 1-year project seeks to develop a novel tandem mass spectrometry method to detect and measure heparan sulfates from hippocampal brain

Read More

CCEH P&F awarded to UWMDI Investigator Kimberly Alonge, PhD

The Co-operative Center for Excellence in Hematology has awarded Dr. Kimberly Alonge a pilot and feasibility award for her project entitled “Investigation of versican mediated recruitment of peripheral myeloid cells into the hypothalamus during diet induced obesity.” This 1-year project seeks to understand the functional role for hypothalamic proteoglycans in the recruitment and migration of

Read More

UWMDI Investigator Dr. Laura Crisa is the Program Director of a new multi-PI R01 award from the National Institute of General Medical Sciences (NIGMS). The award will support a multi-disciplinary research project in collaboration with UWMDI Investigator Dr. Vincenzo Cirulli, and collaborator Dr. Cole DeForest

UWMDI Investigator Dr. Laura Crisa is the Program Director of a new multi-PI R01 award from the National Institute of General Medical Sciences (NIGMS). The award will support a multi-disciplinary research project in collaboration with UWMDI Investigator Dr. Vincenzo Cirulli, and collaborator Dr. Cole DeForest (UW Chemical Engineering) to develop innovative strategies for the transplantation

Read More

UWDI Graduate Student Chelsea Faber receives PhD

Molecular Medicine and Mechanisms of Disease (M3D) Program graduate student Chelsea Faber successfully defended her PhD thesis last week to earn her PhD. Dr. Faber joined the UWDI in 2015 under the mentorship of Gregory Morton, PhD and Michael Schwartz, MD. Please join us in extending our congratulations to Chelsea on this achievement.

Read More

UWMDI Investigator, Dr. Vincenzo Cirulli co-authors a new study with the research team of Dr. Domenico Accili at Columbia University (New York, NY). The study published in Molecular Metabolism.

Dr. Vincenzo Cirulli co-authors a new study with the research team of Dr. Domenico Accili at Columbia University (New York, NY). The study, published in Molecular Metabolism, identifies the Cytochrome b5 reductase (Cyb5r3) as a critical regulator of FoxO1-dependent mitochondrial function that protects pancreatic β-cells from nutritional and oxidative stress. Accordingly, mice with altered Cyb5r3 expression revealed impaired insulin secretion, glucose intolerance and diet-induced

Read More