Research Laboratories

Bornfeldt Laboratory

The Bornfeldt laboratory is dedicated to understanding the cellular and molecular mechanisms of diabetes-accelerated cardiovascular disease, so that these complications can be effectively treated or prevented.

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Chait Laboratory

The Chait laboratory focuses on lipoprotein-proteoglycan interactions in atherogenesis; the role of diabetes in the pathogenesis of macrovascular disease; and the links amongst obesity, inflammation, insulin resistance and atherosclerosis.

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Cirulli Laboratory

The Cirulli laboratory is committed to understanding mechanisms of cell-cell and cell-matrix interactions in pancreatic islet cell development and function.

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Crisa Laboratory

The Crisa laboratory seeks to understand the basic mechanisms by which blood vessels and myeloid immune cells may drive growth and regeneration of pancreatic islets during development and in diabetes.

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den Hartigh Laboratory

The den Hartigh laboratory is dedicated to understanding the impact of fatty acids and inflammatory mediators on adipocyte biology during the development of obesity and subsequent weight loss.

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Dorfman Laboratory

The Dorfman laboratory investigates the protective role of sex steroids in hypothalamic inflammation and obesity.

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Heinecke Laboratory

The Heinecke is dedicated to understanding the structure and function of HDL (good cholesterol), and to predicting the risk of cardiovascular disease in diabetic patients and other subjects at high risk of atherosclerosis.

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Hirsch Laboratory

The Hirsch laboratory investigates new drugs and technologies (including closed loop insulin infusion) for the treatment of diabetes.

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Hull Laboratory

The Hull laboratory investigates the critical role of the islet in diabetes pathogenesis, and how novel aspects of the islet milieu contribute to failure of the islet β cell.

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Kahn Laboratory

Our research involves both basic and clinical investigation and is focused on furthering our understanding of the pathophysiology, prevention and treatment of type 2 diabetes and related disorders.

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Kanter Laboratory

The Kanter laboratory investigates molecular mechanisms that result in complications of diabetes.

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Kim Laboratory

The Kim laboratory focuses on nitric oxide (NO), a crucial molecule involved in maintaining vascular homeostasis.

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Morton Laboratory

The Morton laboratory examines the role of the brain in the regulation of energy balance and glucose metabolism and how defects in this control system may contribute to the development of obesity, insulin resistance and diabetes.

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Page Laboratory

The Page laboratory is dedicated to developing the first hormonal form of contraception for men.

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Rubinow Laboratory

The Rubinow laboratory is dedicated to better understanding the metabolic effects of nuclear receptor ligands including sex steroids and retinoic acid.

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Scarlett Laboratory

The Scarlett laboratory investigates the mechanisms whereby FGF1 action in the brain induces sustained remission of diabetic hyperglycemia.

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Schur Laboratory

The Schur laboratory seeks to understand how the brain regulates appetite. In humans, social, psychological, physiologic, and other factors influence appetite and food intake.

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Schwartz Laboratory

The Schwartz laboratory investigates the role of the brain in the control of both energy balance and blood glucose levels with a focus on how defects in these systems contribute to the pathogenesis of obesity and diabetes.

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Shao Laboratory

The Shao laboratory is dedicated to understanding the pathways for the generation of dysfunctional HDL and the roles of dysfunctional HDL in the pathogenesis of atherosclerosis, diabetes, and other inflammatory diseases in humans.

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Sweet Laboratory

The Sweet laboratory investigates regulation and impairment of insulin secretion in type 2 diabetes; pancreatic beta cell death; metabolic basis of inflammation and T cell calcium metabolism in type 1 diabetes.

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Tang Laboratory

The Tang laboratory is dedicated to understanding the molecular mechanisms of diabetes and diabetes-associated cardiovascular disease.

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Thaler Laboratory

The Thaler laboratory seeks to discover new brain-based treatments for obesity and diabetes.

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Vaisar Laboratory

The Vaisar laboratory examines the role of inflammation in the development and progression of cardiovascular disease.

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