Support Us Join Trial

CATT1

Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes: A 26-Week Double-Blind, Randomized, Placebo-Controlled Phase 3 Study (CATT1)

A solid, uniform light blue color fills the entire image without any patterns, objects, or text visible.

Study Description

IRB #

00254596

NCT #

NCT06334133

Principal Investigator

Dr. Subbulaxmi Trikudanathan

Study Location

UW Medicine Diabetes Institute

This is a phase 3 trial of the investigational drug, cadisegliatin, as an additional treatment to insulin for participants with type 1 diabetes mellitus. The goal of the study is to see if cadisegliatin can reduce the occurrence of low blood sugar compared to placebo (insulin alone). Participants will be asked to attend 11 in-person study visits and up to 11 telephone calls over 9 months, but will take the study drug continuously for 26 weeks during that period. Participants will be asked to use study provided devices, including a continuous glucose monitor and receiver, ketone meter and blood glucose meter, to measure their glucose levels. Study visits will include activities such as reviewing patient health history, measuring vital signs, and collecting blood and urine samples.

Study Details

FAQ Title

Learn more about  how you can contribute to important research by volunteering for CATT1

Who Can Participate?
  •  Must be 18 years or older
  • Individuals diagnosed with Type 1 Diabetes Mellitus for a minimum of 3 years
  • Must be using a CGM device for at least 3 months prior to starting the study
  •  Cannot be using continuous subcutaneous insulin infusion (closed-loop pump symptoms are prohibited); must be using only manual pump mode or multiple daily injections of insulin
  • Cannot be using any non-insulin anti-diabetic therapies (Metformin, GLP-1, SGLT2 inhibitors, etc)
  • Other requirements: Participants must use a form of highly effective contraception if they or their partner are capable of becoming pregnant for the duration of the study
Compensation Provided

You will be paid for your time. If you complete all study visits, you will be paid $1,265.00. Additionally, you will be reimbursed for the cost of parking.

Contact Study Team

Interested? 👉 Send an email or text message to the contact below
Contact Name: Josephine Stenn
Phone Number: 541-399-4004
Email: jstenn@uw.edu

Contact the Study Team - vTv

Name(Required)
Email(Required)
Preferred Method of Contact (email, phone call, text)