IMST

Our study is testing if high-resistance inspiratory muscle strength training can help lower blood pressure and improve heart and kidney health in young people with type 2 diabetes or with risk factors for type 2 diabetes. We will use a set of tests including blood and urine tests, measurements of blood vessel stiffness, and assessments of small samples taken from the lining of the blood vessel wall. The goal of our study is to determine if high-resistance inspiratory muscle strength training could be an easy, effective, and well-tolerated way for young people at risk of elevated blood sugar to stay healthy and reduce the risk of heart and kidney disease.

Duration

The duration of the study would be 90 days, after eligibility has been confirmed with a screening visit and the baseline visit has been completed.

What You Will Do

If you join the study, you will:

• complete a total of eight (8) study visits
• use the POWERBreath pressure threshold training for 12 weeks
• provide blood, urine samples and complete all required tests
• undergo a physical examination, pubertal staging, have vital signs and body measurements taken
• have body composition assessed, have arterial stiffness and endothelial function tested
• have blood and urine samples collected
• wear 24 hours ambulatory blood pressure monitor after visit 2 and 8

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